Company: The University of Manchester
Job title: Senior Group Leader & Professor of Cell Biology, Cancer Research UK Manchester Institute
Dr. Angeliki Malliri completed my bachelors degree in Biology in the University of Patras, Greece and obtained her PhD from the University of Crete, Greece. She worked as a postdoctoral scientist in the Beatson Institute for Cancer Research, Glasgow, UK and the Netherlands Cancer Institute in Amsterdam. She established my independent research group in 2004 in Cancer Research UK Manchester Institute, UK. The focus of their current research is the role of the small GTPase RAC and its regulators in lung tumour formation and progression, including lung tumourigenesis initiated by mutant KRAS. They have also recently instigated a program of research addressing KRAS-mutant isoform selective functions in lung cancer development.
The Role of the Activator of the Small GTPase RAC, TIAM1, in Mutant KRAS Driven Lung Adenocarcinomas 12:30 pm
• The small GTPase RAC has been shown to be required for KRAS-induced lung tumourigenesis • TIAM1, one of the RAC activators, is a RAS effector protein • The role of TIAM1 in the formation and progression of mutant KRAS-driven lung adenocarcinoma and its mechanism of action will be discussedRead more
day: Day Two