The Role of the Activator of the Small GTPase RAC, TIAM1, in Mutant KRAS Driven Lung Adenocarcinomas

Time: 12:30 pm
day: Day Two


• The small GTPase RAC has been shown to be required for KRAS-induced lung tumourigenesis

• TIAM1, one of the RAC activators, is a RAS effector protein

• The role of TIAM1 in the formation and progression of mutant KRAS-driven lung adenocarcinoma and its mechanism of action will be discussed